I haven't used anything but Aquamira for the last 10 years (even on the grossest water imaginable). But being a lazy and impatient sort, I have been on the lookout for something easier for a long time. And I think I may finally have found it:
https://www.rei.com/product/100537/kata ... filter-set
They also sell 1-, 2- and 3-L bottles that you can screw the filter top into. No waiting ever. No dealing with "dirty" and "clean" bottles. No hoses. If you're hiking in an area with a lot of water (I know, that sounds mythical in Arizona, but there are such places), you don't have to carry any water at all.
I'm picking up one of these next time I go to REI. I'll report back on how it works.
We used the BeFree with a 1-L Seeker bottle from Hydrapak for ~170 miles of backpacking in the Uinta Mountains (Utah) and Grand Teton NP. Loved the filter--super easy to use, and if you are in an area with abundant water (yeah, that rules out a lot of Arizona), you can just fill the bottle and drink from it without doing any manual filtering.
The big advantage of this system, as I see it, as that you don't have to carry any water if you don't want to. For a lot of the Uintas, I carried no water--just dipped and sipped at stream crossings now and then (this helped a lot because we were carrying 7 days of food to start). We had AquaMira as a backup and used that in camp most nights because we're lazy, and mixing a few drops is easier than squeezing 4 L of water through the filter, but the BeFree is going to be our go-to filter for any trail where there's a decent amount of water.
FWIW, reviews I read said that the little 0.5-L bottle that comes with the filter is not durable. I'd pick up something bigger from Hydrapak. There are also 2- and 3-L bottles, but I'm not sure how easy it would be to carry a 2 or 3 L bottle with soft sides--it would probably flop over in the side pocket of a backpacking pack. They might work okay in a daypack.