Hi, welcome to HAZ!
Most wouldn't run those but it sounds like you are capable. The ridgeline would be the most difficult. Steep on each end, constant route finding and a bunch of naggy cactus to dodge. If you do either of the Peralta options I'd take the Dutchman #104 vs going over Fremont Saddle on Peralta #102. The 104 route is longer but less crowded, easier grades and some nice flat sections.
Trail map for reference http://hikearizona.com/map.php?X=17
If you can get a shuttle ride Tule to Peralta
is bomb diggity. I'm not a trail runner so it took 17 hrs. We did run a few miles at the end on the #104 I mentioned above as it just begs it. Route finding on this would be most critical. At 36-38 miles in the remote backcountry you can get into serious trouble.
"Peralta to Canyon Lake" or "Tule to Peralta" will take you through a little catclaw country. I'm not a fan of pants but they save skin.
There isn't much catsclaw on your 1(direct over Fremont) or 3 option. The cactus on the ridgeline are dodge obstacles. Pincushion, barrel, hedgehog, agave, ocotillo, etc.