@KabukiMan
Absolutely can do it self-supported and the latest record was. He even tracked how long he was in each store (also tons of video but yeh). It's obviously not something everyone or the vast majority of people can do, of course...
For your questions:
1. Not really. I've not seen bears on that side of the supes but even when I'm in areas with bears in AZ, I still don't bother with bear spray. Just not needed for what we have here. Other than that, standard smarts apply: if your rummaging around rocks, be on the lookout for scorpions. Watch out for snakes; they're mostly bruminating right now but that's "mostly".
2. I'll hang my food sometimes, especially if I'm backpacking somewhere more ON the beaten trail like this, but it's just for rodents; no bear hang needed. Just find a shrub or tree to get your stuff off the ground.
3. I personally prefer it CCW. You should be able to find water at Whisky Spring, which is about 5.5miles going CCW, and then again at La Barge at 8.5ish and Charleboi almost 10 miles in. Bluff Spring is also generally reliable with recent water reports even in this dry year showing it's going; about 13.5 miles in.
4. There's nothing "formally" established but you'll see plenty of areas that have been used and are packed down because of it/have fire rings/etc. Always better to use one of those vs establishing a new one; there's tons in the supes. Your camping plan sounds fine; there's sort of two established spots right near Whisky that are nice and tucked into the cottonwoods. Only "downside" is because it's in this tucked away little spot, it's darker and a little colder. Good be pros or cons, depending on how you look at it. Near Charleboi, tons of great camping right near the spring or tons of spots in that mile west along the creek bed.